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Home > Custom Synthesis of Biologicals
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Custom Synthesis (Biologics)
ACC specializes in the following areas of biological custom synthesis:
ACC Corp specializes in the synthesis of API's and Intermediates by biotransformation as well as synthesis of bio-enzymes for industrial applications. We offer custom fermentation for strains or blends of strains of microorganisms specific to your research activities.
Our areas of expertise include:
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Fermentation optimization for genetically modified organisms (GMO) and non-GMO done in the batch mode or the fed-batch mode (with E. coli / Yeast / Fungi)
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Isolation and purification of biomolecules using chromatography
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Immobilization technologies (whole cell / enzymes) using any of the following methods:
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Entrapment / Encapsulation technologies
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Customized polymer supports with epoxy functionality
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Cross linked enzyme aggregates (CLEA)
We can help you in the following areas:
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Downstream purification services such as concentration of cell mass, culture filtrate as well as protein isolation and characterization
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Media development and optimization
The end products would be provided to you in the form of liquids, as a paste, frozen or lyphilized.
Complete confidentiality is assured for every project undertaken by ACC Corp.
We provide custom peptides with modifications to meet your specific requirements. These could include:
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Simple to complex
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Linear to cyclized
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Long peptides
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Modifications such as biotinylation, phosphorylation, dye labeling etc.
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Bioconjugation with proteins
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Different purity levels and with different scales
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N-terminal acylation
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C-terminal amidation
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Conjugation to KLH, BSA, ETC
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Incorporation of unusual amino acids
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Peptide libraries
Synthesis is carried out using optimized FMOC and BOC methodologies. Purification is carried out using HPLC columns. ALL products come with full documentation including COA, MS and HPLC.
Complete confidentiality is assured for every project undertaken by ACC Corp.
We carry about 10,000 polyclonal and monoclonal antibodies for researchers in academia, industry, diagnostics and pharma. The antibodies we offer target cancer specific surface antigens, GPCR's, glycoproteins, peptides, proteins as well as hormones and their growth factors. They are designed for use in various applications such as functional assays, antibodies for immunoprecipitation, IHC, IF, flow cytometry, western blot, immunofluorescence, immuno-cytochemistry, immunohistochemistry and flow cytometry and ELISA.
We can make from micro grams scale to up to gram scale.
Complete confidentiality is assured for every project undertaken by ACC Corp.
At ACC we work with you to develop protein targets specific to your requirements. These could include:
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Highly purified grades of proteins
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Full length or truncated form of the target
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Tagged or untagged proteins
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Proteins with high biological activity
The proteins can be synthesized in micro-gram to gram scale per your requirement. They are designed for use as biomarkers, diagnostic test proteins or antigens.
Complete confidentiality is assured for every project undertaken by ACC Corp.
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